The headquarters of IDRC are located at 2C Nakasero Hill Road and houses Finance and Administration, Regulatory department, Data Center and the Research Offices. The Molecular laboratory, located at Mulago Hospital Complex serves all of our clinical projects in Uganda by providing confirmatory expert malaria microscopy for studies in Kampala and at our field sites and performing related molecular studies.
The Tororo Research Clinic started in 2007 with Tororo Child Cohort (TCC) study, which was aimed at studying interactions between HIV and Malaria. The facility also runs HIV and malaria trials aimed at evaluating methods to prevent malaria in children and pregnant women. The Tororo research clinic houses the state of the art immunology and parasitology research laboratories and a data center.
The Mbarara office was opened early 2011 to host the SEARCH (Sustainable East African Research for Community Health) pilot studies. The SEARCH collaboration was established to conduct community based research with global partners in health, economics and education that catalyses movement to the Millennium Development Goals. The Mbarara office also hosts the IBIS and Mobility studies.
The Mbale site was opened in June 2013 as a second SEARCH site. It also hosts the Mobility Study.
Is located at Masafu General Hospital, Busia District. This site opened in 2016 to host the Birth Cohort 3, double blinded randomized control trial comparing the risk of any adverse birth outcome in HIV-negative pregnant mothers living in Busia district, Uganda.
Nagongera site is located at Nagongera Health Center IV, which serves Nagongera sub-county in Tororo district in eastern Uganda. Nagongera sub-county is predominantly a rural setting with very high malaria transmission. Just like Kihihi site, the site is also well equipped with participant consultation rooms for cohort study participants, laboratory for malaria microscopy and blood sample collection/processing for immunology studies, and mosquito sample collection/processing for entomology studies. Activities at this site include a cohort study to estimate incidence of malaria, entomology studies to measure malaria transmission, and cross-sectional surveys to estimate prevalence of malaria.
UMSP sentinel sites for malaria surveillance
The Uganda Malaria Surveillance Project (UMSP) was formed in 2001 and is administered by IDRC. The purpose of forming UMSP was to establish and implement a multi-site surveillance system in Uganda for the evaluation of malaria-associated morbidity and mortality and the efficacy and safety of available antimalarial therapies, and to build local capacity with the goal of providing sustainable progress in malaria control. In 2006, Uganda Malaria Surveillance Program (UMSP) with support from the USAID/CDC through the Presidents Malaria Initiative (PMI), started a sentinel site surveillance at six level IV health facilities located in six districts in Uganda. The goal of the program is to provide high quality malaria surveillance data supplementing the national Health Management Information Systems (HMIS). In 2010, UMSP expanded its malaria surveillance program to include an inpatient malaria surveillance system involving 6 government hospitals located in a district with outpatient sentinel sites. With growing demand for data representative of a wider coverage, UMSP expanded the malaria surveillance program from six sentinel sites to 21 Malaria Reference Centers (MRCs) located in 21 districts. In-addition to reporting key malaria indicators over a wider area, the current program relies on a sustainable approach to malaria surveillance that could be replicated through the national HMIS. Over the years, and to date UMSP continues to play a key role in Uganda’s malaria control efforts providing quality malaria surveillance data informing policy makers, and partners on disease burden, impact of interventions like IRS, and ITNs on disease prevalence, and case management practices. Last but not least, the surveillance program has in itself served as an intervention directly improving patient care at participating sites.