INTEGRATED HIV/HTN Project:
Leveraging the HIV Platform for Hypertension Control in Uganda.
Study Period: March 2020-February 2025
INTEGRATED HIV/HTN (Leveraging the HIV Platform for Hypertension Control in Uganda) is a five-year project funded by the Second European and Developing Countries Clinical Trials Partnership (EDCTP2) Grant Number: CSA2018HS-2518 to test the effectiveness of an integrated HIV/HTN care model in 26 districts in south-western Uganda. This project is implemented by a consortium led by the Infectious Diseases Research Collaboration (IDRC) in collaboration with the London School of Hygiene and Tropical Medicine (LSHTM), the Uganda Heart Institute (UHI), the Ministry of Health Uganda (MoH) and Makerere University.
There is a high burden of hypertension among HIV and non-HIV-infected people in Uganda, ranging from 15-30%. Yet, the capacity to diagnose, treat and prevent hypertension (HTN) remains sub-optimal. The double jeopardy of HIV and hypertension likely increases the risk of complications such as stroke, coronary artery disease and kidney failure. Less than 5% of people with hypertension are thought to receive regular care; thus, increasing access to care will require its integration into primary health care and HIV clinics, thus reducing co-occurring hypertension-related morbidity and mortality
The project will evaluate the effectiveness of the integrated HIV and HTN care model in selected districts and health facilities in South Western Uganda. It aims at increasing awareness of hypertension, improving hypertension control and improving quality of life for HIV patients and non-infected populations in an integrated manner and ultimately contribute to reducing the overall prevalence of hypertension in Uganda.
Objectives
- Determine the effectiveness of the integrated HIV/HTN care model on HTN screening, HTN control and dual HIV/HTN control in the HIV clinics;
- To assess the barriers and facilitators of the integrated HIV/HTN care model among National Disease Control Programs, middle-level health district managers, clinic-level PHC leaders, providers, and patients; and
- Determine the cost, cost-effectiveness and incremental gain costs of the integrated HIV/Hypertension care model approach.
Study Site: 96 districts in Ankole, Kigezi, Bunyoro- Tooro
Collaborators: Infectious Diseases Research Collaboration (IDRC), Uganda Ministry of Health (MoH), Makerere University, London School of Hygiene & Tropical Medicine (LSHTM) and Uganda Heart Institute (UHI)
Principal Investigator: Jane Kabami
Study Sponsor: EDCTP
